Diabetes Mellitus Type 2 is a nightmare that will haunt anyone that it sets its eyes on for life.
By Robert P. Tracy
There is no cure for this chronic disease, making the battle against it a lifelong task. Since there is no effective cure for it, knowing what you can do to help yourself is important to prevent the development of complications and secondary diseases. Ignorance is something this world can live happily without, and with today’s way of life, knowing is everything. That is why it is important to arm yourself with the knowledge of this disease, and in this article you’ll know more about the first line of treatment for diabetes which is Metformin.
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Metformin belongs in the biguanide class of oral hypoglycemic agents (OHAs). This drug classification is also called anti-hyperglycemic drugs or anti-diabetic drugs, the latter raising the eyebrows of some experts. When diet and exercise prove to be insufficient in controlling this disease, Metforrmin or other OHAs are prescribed. (Metformin was discovered in the flower of a Frnch Lilac flower. Click here to read about it.)
Different classes of OHAs work in various ways to control the blood sugar. But due to Metformin’s inability to cause hypoglycemia (blood sugar below normal level), many doctors tend to go for this drug over the others. As a matter of fact, metformin was found out to be the most prescribed oral hypoglycemic agent last year.
This drug is very favorable for overweight and obese patients because unlike other anti-diabetic drugs including insulin, it does not cause obvious weight gain. It also helps in decreasing the levels of bad cholesterol and triglycerides in the blood, which helps in preventing complications like heart problems.
Common side effects of this drug involve but are not exclusive to the gastrointestinal system. These include nausea, vomiting, loose bowel movement, bloating, gas, and decreased appetite. The majority of the cases experience gradual decrease of the side effects. Home tips and tricks to prevent these side effects may involve taking the drug with meals. Some people who have been on the medication claim that maintaining a low carbohydrate diet can help prevent some of these side effects. Adjusting your eating habits to coincide with your medication can also help.
A serious side effect of this drug rarely occurs. It is called lactic acidosis, which is caused by the accumulation of lactic acid in the blood stream. This results when glucose production is done anaerobically by the body. In lactic acidosis, the excess pyruvate derived from glucose is directly converted to lactate. These are released from the cells into the bloodstream where they accumulate over time. A value higher than 5 mmol/L and decreased blood pH levels are indications of this phenomenon. Mortality is very high if it is not treated within 24 hours. Signs and symptoms of lactic acidosis include rapid and deep breathing, altered mental status, vomiting and abdominal pain.
The most common and difficult, personal side effect is hiarrhea. Click here for an interresting article sharring som eof the detailes of this problem.
Before taking the medicine, it is important to inform your physician about any other drugs you are taking to prevent fatal drug interactions. Relay also information about past or present health conditions such as heart attacks, congestive heart failures, heart ischemia or infarction, liver cirrhosis, fatty liver, hepatitis, kidney problems, systemic infection, and other health problems that are related to decreased oxygenation of the cells.
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